Microfluidics, Lab- & Organ-on-a-Chip – About the Group

Since the first publication of a microanalytical device in 1979, a booming international activity is seen in the field of microfluidics for health, food, water and environmental analysis. Microfluidics and its expansion to Lab- and more recently to Organ-on-a-Chip is maturing as a field and is showing a significant market growth. Our group, with a gradually growing activity since 2005, supported by several national and European competitive projects, has been very active in the field, starting from digital microfluidics, expanding to the development of microfluidics for DNA amplification, reagent mixing, bacteria capture and DNA purification, more recently focusing on extremely innovative lab-on-chips for food safety and health applications, and lately on the development of an organ-on-a-chip platform for constituting in vivo cellular environments. The work is being continuously supported by indispensable computer simulation to significantly shorten the long process of design and fabrication. The novelty in our work is based but not limited to the incorporation in microfluidics of nanotextured and plasma-functionalized surfaces as well as the exploitation of printed circuit boards as building platforms for industrially produced, low-cost microfluidics for biochemical analysis. This has been demonstrated by the award of six (6) national and European patents in the field of microfluidics/LoC. One of our innovations, i.e. the manufacturing of microfluidics on a printed circuit board, has been recognized by the European Commission’s Innovation Radar and it is considered as “business ready”. Furthermore, our innovation on the incorporation in microfluidics of plasma nanotextured and functionalized surfaces is the main technology exploited in a NCSR “Demokritos” spin-off, Nanoplasmas PC.

Timeline of the group achievements