Research Interests : Sorption and diffusion in polymers; characterization of polymers and their composites; polymer-based controlled release systems; mechanisms of drug release

Email : k.papadokostaki@inn.demokritos.gr

Research Interests
Sorption and diffusion in polymers; characterization of polymers and their composites; polymer-based controlled release systems; mechanisms of drug release
Position
Researchers
Telephone
+30 210 650 3661 / 3639
CV English
About/Biography
Dr Kyriaki Papadokostaki was born in Heraklion-Crete, Greece (1956) and graduated from the Chemistry Department of the National University of Athens in 1979. At the same year, she earned a scholarship from NCSR “Demokritos”, where she worked as a post-graduate student under the supervision of Dr J. H. Petropoulos in the area of diffusion in polymers. She received her PhD in Chemistry from the University of Athens in 1986. From 1986 to 1995 she continued working at “Demokritos” as a collaborating researcher at the Institute of Nuclear Technology and Radiation Protection (in the framework of a European Research Project for the management and storage of radioactive waste) and at the Laboratory of Transport of Matter Phenomena in Polymers of the Institute of Physical Chemistry. In 1995 she was appointed as a staff Researcher at the Institute of Physical Chemistry. Since 2012 she is a research director at the Institute of Nanoscience and Nanotechnology of the NCSR “Demokritos”. She has authored or co-authored more than 55 publications in refereed journals and 4 book chapters. She has also successfully supervised 4 PhD students and participated in various funded research projects. Her research interests include sorption and diffusion of micromolecules in polymeric materials; controlled release of drugs and other bioactive solutes from matrix-type systems; elucidation of drug release mechanisms; multicomponent transport in polymers; sorption and diffusion of ions in polymers and porous media; thermal characterization of polymers.

SELECTED PUBLICATIONS

1. Panou, A.I., Mantes, N., Papadokostaki, K.G., Sanopoulou, M. Solute permeability of elastomeric films containing dispersed swellable hydrophilic particles: A composite material approach. Eur. Polymer J. 93, 471–479 (2017).
2. Sanopoulou, M., Papadokostaki, K.G. Controlled drug release systems: Mechanisms and kinetics. In Biomedical Membranes And (Bio)artificial Organs (Stamatialis D. ed.), 1-33 (World Scientific Publishing Co. Pte. Ltd, 2017).
3. Papadokostaki, K.G., Minelli, M., Doghieri, F., Petropoulos, J.H. A fundamental study of the extent of meaningful application of Maxwell's and Wiener's equations to the permeability of binary composite materials. Part II: A useful explicit analytical approach. Chem. Eng. Sci. 131, 353-359 (2015).
4. Panou, A.I., Papadokostaki , K.G., Tarantili, P.A., Sanopoulou, M. Effect of hydrophilic inclusions on PDMS crosslinking reaction and its interrelation with mechanical and water sorption properties of cured films. Eur. Polym. J. 49, 1803-1810 (2013).
5. Petropoulos, J.H., Papadokostaki, K.G., Sanopoulou, M. Higuchi’s equation and beyond: Overview of the formulation and application of a generalized model of drug release from polymeric matrices. Int. J. Pharm. 437, 178-191 (2012), mini review.
6. Soulas, D.N., Papadokostaki, K.G. Regulation of proxyphylline’s release from silicone rubber matrices by the use of osmotically active excipients and a multi-layer system. Int. J. Pharm. 408, 120-129 (2011).
7. Papadokostaki, K.G., Savidou, A. Study of leaching mechanisms of caesium ions incorporated in Ordinary Portland Cement. J. Hazardous Materials 171, 1024-1031 (2009).
8. Hasimi, A., Stavropoulou, A., Papadokostaki, K.G., Sanopoulou, M. Transport of water in polyvinyl alcohol films: effect of thermal treatment and chemical crosslinking. Eur. Polymer J. 44, 4098-4107 (2008).
9. Papadokostaki, K.G. , Stavropoulou, A., Sanopoulou, M., Petropoulos, J.H. An advanced model for composite planar three-layer matrix-controlled release devices. Part I. Devices of uniform material properties and non-uniform solute load. J. Membrane Sci. 312, 193-206 (2008).
10. Papadokostaki, K.G. Combined Experimental and Computer Simulation Study of the Kinetics of Solute Release from a Relaxing Swellable Polymer Matrix. II. Release of an Osmotically Active Solute. J. Applied Polym. Sci. 92, 2458-2467 (2004).