Functional surfaces can find applications as antibacterial surfaces, as separation membranes, as low friction/adhesion or high binding surfaces. While polymeric materials are a very common solution, the rapidly increasing production of disposable plastic products and the excessive use of fossil resources have created the necessity for alternative production models. The development of integrated biorefinery concepts within the circular bioeconomy era, could provide the solution in this urgent problem. Natural polymers such as Bacterial cellulose (BC) can replace typical polymers. Yet, several drawbacks are delaying the uptake of such green materials, a) the long-term cultivation duration, b) the high cost associated with the fermentation feedstock and c) the absence of micro-nanotexturing and surface functionalization tools in order to tune on demand the properties of the biopolymers, since most studies have dealt with chemical or synthesis methods to improve the properties of BC. EXERCISE focuses on providing solution on this three-factor problem by proposing a new concept for the production of BC which will address current production limitations, coupled with the application of dry and environmentally friendly micronano texturing techniques (plasma texturing & BC guided assembly using textured flexible molds) to tune on demand the structural and chemical properties of BC. The materials which will be developed will be used a) as antibacterial surfaces in domestic, health and other applications in order to reduce the extensive use of antibiotics causing the antimicrobial resistance and b) as superhydrophobic biomembranes for separation applications. Two organizations with complementary expertise and infrastructure are collaborating to address the objectives of EXERCISE, INN-Demokritos and DFNS-University of the Aegean.