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RESEARCH INTERESTS

Liposomes, dendritic polymers, carbon dots, drug delivery, biomimetic synthesis, superhydrophobic nanoparticles, 3D scaffolds, liquid crystals

ABOUT/BIOGRAPHY

Dimitris Tsiourvas was born in 1962 in Larissa, Greece. He studied Chemical Engineering at the National Technical University of Athens (1984) and obtained his PhD (NTUA, Chemical Engineering School, 1992) working in the area of polymeric liquid crystals under the supervision of Dr C. M. Paleos in NCSR “Demokritos”. He worked in the plastics processing industry ARGO SA, Greece (1988-1995), and then joined the Institute of Physical Chemistry of NCSR “Demokritos” in 1995 as a Researcher. He is head of the laboratory of Functional Nanomaterials of Organized Structure

(2007-today). He is the co-author of more than 120 publications in peer-reviewed journals and of 2 books chapters, co-inventor of 4 international and 6 national patents and has participated in 11 European and 12 Greek research projects. He is currently an editorial board member in Pharmaceuticals (ISSN 1424-8247). His current research interests mainly include synthetic and physicochemical aspects of liposomes, dendrimers, carbon dots and hybrid organic/inorganic nanomaterials for specific applications, including:

  • Preparation and characterization of liposomes and their application as drug carriers
  • Functionalization and characterization of dendritic polymers and their application as controlled release and targeted drug delivery systems
  • Preparation, functionalization and characterization of carbon dots and their application as imaging agents of cancerous cells
  • Synthesis of hybrid organic/inorganic nanoparticles based on an environmentally friendly biomimetic processes employing dendritic polymers
  • 3D nanohydroxyapatite/biopolymer scaffolds of complex geometries for bone tissue engineering applications
  • Superhydrophobic and oleophobic fluorinated silica nanoparticles and their application as surface coatings
  • Synthesis and characterization of liquid crystals and liquid crystal/nanoparticle composites

WEBSITES

https://orcid.org/0000-0002-4112-7097

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https://scholar.google.com/citations?user=pCuCxWEAAAAJ&hl=el

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PUBLICATIONS

Kaminari, A., Nikoli, E., Athanasopoulos, A., Sakellis, E., Sideratou, Z. and Tsiourvas, D., Engineering mitochondriotropic carbon dots for targeting cancer cells Pharmaceuticals, Volume 14, Article Number: 932, 2021 [doi]

Stagni, V., Kaminari, A., Sideratou, Z., Sakellis, E., Vlahopoulos, S.A. and Tsiourvas, D., Targeting breast cancer stem-like cells using chloroquine encapsulated by a triphenylphosphonium-functionalized hyperbranched polymer International Journal of Pharmaceutics, Volume 585, Article Number: 119465, 2020 [doi]

Lykogianni, M., Papadopoulou, E.-A., Sapalidis, A., Tsiourvas, D., Sideratou, Z. and Aliferis, K.A., Metabolomics reveals differential mechanisms of toxicity of hyperbranched poly(ethyleneimine)-derived nanoparticles to the soil-borne fungus Verticillium dahliae Kleb Pesticide Biochemistry and Physiology, Volume 165, Article Number: 104535, 2020 [doi]

Kyrou, C., Tsiourvas, D., Kralj, S. and Lelidis, I., Effect of superhydrophobic nanoplatelets on the phase behaviour of liquid crystals Journal of Molecular Liquids, Volume 298, Article Number: 111984, 2020 [doi]

Eleftheriou, K., Kaminari, A., Panagiotaki, K.N., Sideratou, Z., Zachariadis, M., Anastassopoulou, J. and Tsiourvas, D., A combination drug delivery system employing thermosensitive liposomes for enhanced cell penetration and improved in vitro efficacy International Journal of Pharmaceutics, Volume 574, Article Number: 118912, 2020 [doi]

Chatzipetros, E., Yfanti, Z., Christopoulos, P., Donta, C., Damaskos, S., Tsiambas, E., Tsiourvas, D., Kalogirou, E.-M., Tosios, K.I. and Tsiklakis, K., Imaging of nano-hydroxyapatite/chitosan scaffolds using a cone beam computed tomography device on rat calvarial defects with histological verification Clinical Oral Investigations, Volume 24, Pages: 437-446, 2020 [doi]

Sideratou, Z., Agathokleous, M., Theodossiou, T.A. and Tsiourvas, D., Functionalized Hyperbranched Polyethylenimines as Thermosensitive Drug Delivery Nanocarriers with Controlled Transition Temperatures Biomacromolecules, Volume 19, Pages: 315-328, 2018 [doi]

Chatzipetros, E., Christopoulos, P., Donta, C., Tosios, K.I., Tsi-Ambas, E., Tsiourvas, D., Kalogirou, E.-M. and Tsiklakis, K., Application of nano-hydroxyapatite/chitosan scaffolds on rat calvarial critical-sized defects: A pilot study Medicina Oral Patologia Oral y Cirugia Bucal, Volume 23, Pages: e625-e632, Article Number: 22455, 2018 [doi]

Tziveleka, L.-A., Ioannou, E., Tsiourvas, D., Berillis, P., Foufa, E. and Roussis, V., Collagen from the marine sponges Axinella cannabina and Suberites carnosus: Isolation and morphological, biochemical, and biophysical characterization Marine Drugs, Volume 15, Article Number: 152, 2017 [doi]

Tsiourvas, D., Papavasiliou, A., Deze, E.G., Papageorgiou, S.K., Katsaros, F.K., Romanos, G.E., Poulakis, E., Philippopoulos, C.J., Xin, Q. and Cool, P., A green route to copper loaded silica nanoparticles using hyperbranched poly(Ethylene imine) as a biomimetic template: Application in heterogeneous catalysis Catalysts, Volume 7, Article Number: 390, 2017 [doi]

Panagiotaki, K.N., Sideratou, Z., Vlahopoulos, S.A., Paravatou-Petsotas, M., Zachariadis, M., Khoury, N., Zoumpourlis, V. and Tsiourvas, D., A triphenylphosphonium-functionalized mitochondriotropic nanocarrier for efficient co-delivery of doxorubicin and chloroquine and enhanced antineoplastic activity Pharmaceuticals, Volume 10, Article Number: 91, 2017 [doi]

Paleos, C.M., Sideratou, Z. and Tsiourvas, D., Drug Delivery Systems Based on Hydroxyethyl Starch Bioconjugate Chemistry, Volume 28, Pages: 1611-1624, 2017 [doi]

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