Integrated polymer-based micro fluidic micro system for DNA extraction, amplification, and silicon-based detection
EU - IST-FP6-STREP-027333 Micro2DNA
The Micro2DNA project dealt with the development of a single device integrated micro system for nucleic acid extraction, mixing steps, purification, PCR amplification, biochemical reactions from biological samples e.g. blood, amplification, and DNA micro array detection in real time. The technologies used were silicon-based for the implementation of the detection and polymer-based for the micro fluidic part. The various modules are integrated within a single device where samples were transported between modules via an enclosed micro fluidic channel system. The whole system was also complemented by dedicated software in order to facilitate the operation of the portable apparatus by general practitioners “packaged” as a portable automated functional system.