RESEARCH INTERESTS

Cyanotoxins, cyanopeptides, cyanobacteria secontary metabolites, bioactive compounds, low and high resolution mass spectrometry, environmental analysis

ABOUT/BIOGRAPHY

Dr Sevasti – Kiriaki Zervou graduated the Chemistry Department (2009) of the National and Kapodistrian University of Athens (UOA), and received her master degree in Chemical Analysis and Quality Control (2011) and her PhD degree in the field of analytical chemistry (2018) from UOA in collaboration with NCSR “Demokritos” under the supervision of Dr. A. Hiskia. She has joined the group of Photo-Catalytic Processes and Environmental Chemistry Laboratory, Institute of Nanoscience and Nanotechnology of NCSR “Demokritos” from 2007 and she has been employed in several national, competitive EU and industrial projects as a research scientist. In addition, she is analyst at the accredited (according to ISO 17025) Laboratory of Environmental Analysis of NCSR “Demokritos”, which is accredited laboratory for the analysis of cyanotoxins and explosives.

      Her research sits at the intersection of environmental chemistry, advanced analytical chemistry, and environmental safety. Her core research interests include:

  • High-Resolution Mass Spectrometry (LC-HRMS): Implementing untargeted analysis and AI-driven computational workflows for compound annotation, molecular networking propagation, in silico fragmentation, and the construction of MS² spectral libraries.
  • Cyanobacterial Toxins & Peptides: Developing advanced tandem MS/MS and HRMS methodologies to isolate, structural elucidate, and identify novel bioactive cyanopeptides and toxic metabolites in freshwater ecosystems.
  • Environmental & Industrial Contaminants: Investigating the occurrence, environmental fate, and degradation pathways of emerging contaminants, taste and odor (T&O) compounds, and primary/secondary explosives in soil and water systems.
  • Material & Chemical Safety Studies: Assessing the elution of hazardous substances and chemical leaching from biomedical and industrial products (such as 3D-printed orthodontic clear aligners) into biological or environmental matrices.
  • Laboratory Quality Management: Implementing and optimizing ISO/IEC 17025 compliance standards for rigorous laboratory operations, validation protocols, and uncertainty estimations.

She has been awarded twice by the Hellenic Mass Spectrometry Society (HMSS) and has earned a grand by the International Mass Spectrometry Foundation (IMSF) and a post-doctoral fellowship by the Greek State Scholarships Foundation (ΙΚΥ). She has participated in four COST Actions (CYANOACTION CA23160 as Grant Awarding Coordinator, WaterTOP COST Action CA18225, CYANOCOST Action ES1105, and NETLAKE (ESSEM) COST Action ES1201). Up to date, she has published more than 30 research papers in international peer-reviewed journals (h-index 19), 3 book chapters and has more than 60 presentations in International Conferences.

https://orcid.org/0000-0003-3049-9351

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PUBLICATIONS

Wang, Junjie, Wen, Yu, Shao, Ying, Schäffer, Andreas, Rojo-Nieto, Elisa, Schmitz, Karla, Jahnke, Annika, Zervou, Sevasti-Kiriaki, Hiskia, Anastasia and Chen, Zhongli, Emerging contaminants in sediments of a tributary to the Yangtze river in the Three Gorges Reservoir Area: Fate, ecological risk assessment, and prioritization for management Journal of Hazardous Materials, Elsevier B.V., Volume 502, 2026 [doi]

Mazur-Marzec, Hanna, Grabski, Michał, Konkel, Robert, Cegłowska, Marta, Cyske, Zuzanna, Gaffke, Lidia, Grabowski, Łukasz, Hiskia, Anastasia, Kajs, Marek, Kaloudis, Triantafyllos, Napiórkowska-Krzebietke, Agnieszka, Pierzynowska, Karolina, Rintz, Estera, Iliakopoulou, Sofia, Walat, Semko, Zervou, Sevasti-Kiriaki, Zielenkiewicz, Monika and Węgrzyn, Grzegorz, Genetic, metabolic and toxicological diversity within Prymnesium parvum (Haptophyte) from Polish waterbodies Water Research, Elsevier Ltd, Volume 282, 2025 [doi]

Pratsinis, Harris, Mavrogonatou, Eleni, Zervou, Sevasti-Kiriaki, Triantis, Theodoros, Hiskia, Anastasia and Kletsas, Dimitris, Natural Product-Derived Senotherapeutics: Extraction and Biological Evaluation Techniques Oncogene-Induced Senescence: Methods and Protocols, Springer US, Pages: 315–359, 2025 [doi]

Stocker, Larissa, Zervou, Sevasti-Kiriaki, Papageorgiou, Spyridon N., Karakousoglou, Stephania, Triantis, Theodoros, Hiskia, Anastasia, Eliades, George and Eliades, Theodore, Salivary levels of eluents during Invisalign™ treatment with attachments: an in vivo investigation Progress in Orthodontics, Volume 25, Pages: 22, 2024 [doi]

Giannakis, Theodoros, Zervou, Sevasti-Kiriaki, Triantis, Theodoros M., Christophoridis, Christophoros, Bizani, Erasmia, Starinskiy, Sergey V., Koralli, Panagiota, Mousdis, Georgios, Hiskia, Anastasia and Kandyla, Maria, Enhancing the Photocatalytic Activity of Immobilized TiO2 Using Laser-Micropatterned Surfaces Applied Sciences, Multidisciplinary Digital Publishing Institute, Volume 14, Pages: 3033, 2024 [doi]

Piel, Tim, Sandrini, Giovanni, Weenink, Erik F.J., Qin, Hongjie, Herk, Maria J. van, Morales-Grooters, Mariël Léon, Schuurmans, J. Merijn, Slot, Pieter C., Wijn, Geert, Arntz, Jasper, Zervou, Sevasti-Kiriaki, Kaloudis, Triantafyllos, Hiskia, Anastasia, Huisman, Jef and Visser, Petra M., Shifts in phytoplankton and zooplankton communities in three cyanobacteria-dominated lakes after treatment with hydrogen peroxide Harmful Algae, Elsevier B.V., Volume 133, 2024 [doi]

Iliadi, Anna, Zervou, Sevasti-Kiriaki, Koletsi, Despina, Schätzle, Marc, Hiskia, Anastasia, Eliades, Theodore and Eliades, George, Surface alterations and compound release from aligner attachments in vitro European Journal of Orthodontics, Oxford University Press, Volume 46, 2024 [doi]

Maria Antonopoulou, Panagiota Bika, Ilias Papailias, Sevasti-Kiriaki Zervou, Androniki Vrettou, Ioanna Efthimiou, George Mitrikas, Nikolaos Ioannidis, Christos Trapalis, Panagiotis Dallas, Dimitris Vlastos and Anastasia Hiskia, Photocatalytic degradation of organic micropollutants under UV-A and visible light irradiation by exfoliated g-C3N4 catalysts Science of The Total Environment, Volume 892, Pages: 164218, 2023 [doi]

Willi, Andreas, Patcas, Raphael, Zervou, Sevasti-Kiriaki, Panayi, Nearchos, Schätzle, Marc, Eliades, George, Hiskia, Anastasia and Eliades, Theodore, Leaching from a 3D-printed aligner resin European Journal of Orthodontics, Oxford University Press, Volume 45, Pages: 244 - 249, 2023 [doi]

Varriale, Fabio, Tartaglione, Luciana, Zervou, Sevasti-Kiriaki, Miles, Christopher O., Mazur-Marzec, Hanna, Triantis, Theodoros M., Kaloudis, Triantafyllos, Hiskia, Anastasia and Dell’Aversano, Carmela, Untargeted and targeted LC-MS and data processing workflow for the comprehensive analysis of oligopeptides from cyanobacteria Chemosphere, Volume 311, Pages: 137012, 2023 [doi]

Zervou, Sevasti-Kiriaki, Hammoud, Noura Alice, Godin, Simon, Hiskia, Anastasia, Szpunar, Joanna and Lobinski, Ryszard, Detection of secondary cyanobacterial metabolites using LC-HRMS in Lake Karaoun Science of the Total Environment, Elsevier B.V., Volume 892, 2023 [doi]

Zervou, Sevasti-Kiriaki, Kaloudis, Triantafyllos, Gkelis, Spyros, Hiskia, Anastasia and Mazur-Marzec, Hanna, Anabaenopeptins from cyanobacteria in freshwater bodies of greece Toxins, MDPI, Volume 14, 2022 [doi]

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