RESEARCH INTERESTS

Synthetic organic chemistry, biomimetic synthesis, natural products and analogs, heterocyclic compounds for biological applications, polyaromatic compounds for nanotechnology

ABOUT/BIOGRAPHY

Dr. Veroniki Vidali obtained her B.Sc. in the Chemistry Department of the National and Kapodistrian University of Athens (1998). Upon graduation, she pursued her PhD (acquired in 2004),  joining the team of professor Elias Couladouros in the Chemistry Laboratory – General Department – Agricultural University of Athens. During her PhD, she worked on the biomimetic synthesis of the family of bisorbicillinoids,  and on the synthesis of trans-anti-6,7-bicyclic systems found in natural oxepane sesquiterpenes, completing the asymmetric construction of the A,B-system of adociasulfate-2 and toxicol A, and the asymmetric synthesis of the natural products (-)-aplysistatin, (+)-12-hydroxy-palisadin B and (+)-palisadin A, and the first asymmetric total synthesis of (+)-palisadin B.  In parallel, she was involved as a research scientist in the design and synthesis of polyaromatic compounds for applications in microlithography. From 2004 to 2007, she worked as a post-doctoral fellow at the Laboratory of Synthesis of Natural Products and Bioorganic Chemistry of the Institute of Physical Chemistry / NCSR "Demokritos", collaborating with the Institute of Microelectronics and Intel Company, working on the design and synthesis of polyaromatic compounds, applied in microlithography. She was also involved in developing a synthetic methodology for bioactive hyperforin analogues. From 2007 to 2017, she worked as a Special Scientific Stuff (Synthetic Chemist) at the Synthesis of Natural Products and Bioorganic Chemistry Laboratory of the Institute of Nanoscience and Nanotechnology at NCSR "Demokritos", where she's a Researcher C Level since 2017. She has co-authored twenty-five (25) research articles in international peer-reviewed journals (h index = 12), one (1) book chapter, and she is a co-inventor in two (2) international patents. She has participated in several research grants, and she's scientific responsible in one. She's a guest editor in 2 peer-reviewed international journals. She has established national and international collaborations. Also, she has launched her own research team, and she has supervised/co-supervised three (3) PhD candidates, nine (9) graduate students (M.Sc.), and two (2) undergraduate students (BSc thesis).  Her main research interests include the total synthesis of bioactive natural products and analogues, organic compounds for biological applications, and polyaromatic compounds applied in nanotechnology.

https://orcid.org/0000-0001-9020-8726

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PUBLICATIONS

Stergiou, I.E., Kambas, K., Poulaki, A., Giannouli, S., Katsila, T., Dimitrakopoulou, A., Vidali, V., Mouchtouris, V., Kloukina, I., Xingi, E., Pagakis, S.N., Probert, L., Patrinos, G.P., Ritis, K., Tzioufas, A.G. and Voulgarelis, M., Exploiting the role of hypoxia-inducible factor 1 and pseudohypoxia in the myelodysplastic syndrome pathophysiology International Journal of Molecular Sciences, Volume 22, Article Number: 4099, 2021 [doi]

Moschona, F., Vagena, A., Vidali, V.P. and Rassias, G., A novel dual organocatalyst for the asymmetric pinder reaction and a mechanistic proposal consistent with the isoinversion effect thereof Molecules, Volume 26, Article Number: 6398, 2021 [doi]

Matiadis, D., Ng, S.-T., Chen, E.H.-L., Nigianni, G., Vidali, V.P., Canko, A., Chen, R.P.-Y. and Sagnou, M., Synthesis and biological evaluation of hydroxylated monocarbonyl curcumin derivatives as potential inducers of neprilysin activity Biomedicines, Volume 9, Article Number: 955, 2021 [doi]

Pitsinos, Emmanuel N., Mavridis, Ioannis and Tzouma, Eirini and Vidali, Veroniki P., Enantioselective Synthesis of Cassane-Type Furanoditerpenoids: Total Synthesis of Sucutiniranes C and D EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Volume 2020, Pages: 4730-4742, 2020 [doi]

Vidali, V.P., Synthesis of natural products and designed organic molecules in anticancer drug development Review of Clinical Pharmacology and Pharmacokinetics, International Edition, Volume 34, Pages: 64-65, 2020 [doi]

Vidali, V.P., Canko, A., Peroulias, A.D., Georgas, E.T., Bouzas, E., Herniman, J.M. and Couladouros, E.A., An Improved Biomimetic Formal Synthesis of Abyssomicin C and atrop-Abyssomicin C European Journal of Organic Chemistry, Volume 2020, Pages: 4547-4557, 2020 [doi]

Soultati, A., Verykios, A., Armadorou, K.-K., Tountas, M., Vidali, V.P., Ladomenou, K., Palilis, L., Davazoglou, D., Coutsolelos, A.G., Argitis, P. and Vasilopoulou, M., Interfacial engineering for organic and perovskite solar cells using molecular materials Journal of Physics D: Applied Physics, Volume 53, Article Number: 263001, 2020 [doi]

Mitsios, A., Chrysanthopoulou, A., Arampatzioglou, A., Angelidou, I., Vidali, V., Ritis, K., Skendros, P. and Stakos, D., Ticagrelor exerts immune-modulatory effect by attenuating neutrophil extracellular traps International Journal of Molecular Sciences, Volume 21, Article Number: 3625, 2020 [doi]

Kapella, A., Gkeka, P., Stellas, D., Vidali, V.P., Papafotika, A., Christoforidis, S., Cournia, Z. and Couladouros, E.A., Design and synthesis of targeted inhibitors of pi3kα as candidate anti-cancer drugs Review of Clinical Pharmacology and Pharmacokinetics, International Edition, Volume 34, Pages: 77-78, 2020 [doi]

Kimbaris, A.C., González-Coloma, A., Andrés, M.F., Vidali, V.P., Polissiou, M.G. and Santana-Méridas, O., Biocidal Compounds from Mentha sp. Essential Oils and Their Structure–Activity Relationships Chemistry and Biodiversity, Volume 14, Article Number: e1600270, 2017 [doi]

Chrysanthopoulou, A., Kambas, K., Stakos, D., Mitroulis, I., Mitsios, A., Vidali, V., Angelidou, I., Bochenek, M., Arelaki, S., Arampatzioglou, A., Galani, I.-E., Skendros, P., Couladouros, E.A., Konstantinides, S., Andreakos, E., Schäfer, K. and Ritis, K., Interferon lambda1/IL-29 and inorganic polyphosphate are novel regulators of neutrophil-driven thromboinflammation Journal of Pathology, Volume 243, Pages: 111-122, 2017 [doi]

Tzouma, Eirini, Mavridis, Ioannis and Vidali, Veroniki P. and Pitsinos, Emmanuel N., Diels-Alder reaction between 1,3,3-trisubstituted-2-vinylcyclohexenes and quinones under exceptionally mild conditions: a concise entry to the cassane-type furanoditerpenoid skeleton TETRAHEDRON LETTERS, Volume 57, Pages: 3643-3647, 2016 [doi]

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