Magnetic Nanostructures for biomedical applications

Magnetic Nanostructures for biomedical applications

The use of magnetic nanoparticles in biomedical applications (e.g. hyperthermia agents, contrast agents, biosensors) has attracted a lot of attention in the recent years. Our group has demonstrated in the previous years the conditions that optimize the heating efficiency (hyperthermia applications) and the MRI signal in various magnetic nanoparticles systems. This activity has started during the funded EXCELLENCE project COMANA (Complex Magnetic Nanostructures) (2012-2015) and it goes on. We are going to continue these studies by investigating novel materials that will enhance the heating efficiency and the signal of the ferrofluids. 

1. Novel Fe oxide based nanostructures with high magnetization and anisotropy values for higher heating and MRI performance

Selected Publications 

Tailoring defects and nanocrystal transformation for optimal heating power in bi-magnetic CoyFe1−yO@CoxFe3−xO4 particles

Nanoscale 14 (2022) 382-401

Vacancy-Driven Noncubic Local Structure and Magnetic Anisotropy Tailoring in FexO−Fe3−δO4 Nanocrystals

Phys. Rev. X  9 (2019) 041044

Susceptibility losses in heating of magnetic core/shell nanoparticles for hyperthermia: a Monte Carlo study of shape and size effects

Nanoscale 7 (2015) 7753

Assembly-mediated interplay of dipolar interactions and surface spin disorder in colloidal maghemite nanoclusters

Nanoscale 6 (2014) 3764

2. Study of the Effect of organic/inorganic coating on the nanoparticles’ properties

The organic or inorganic surfactant coatings at the surface of magnetic nanoparticles are extensively used in order to provide biocompatibility, low-toxicity, colloidal stability in liquid carriers and to prevent agglomeration. We are studying the physical parameters that are influenced by the presence of organic surfactants at the ferrite nanoparticles’ surface (i.e. the magnetic anisotropies, the magnetic moments and the nanoparticle’s charge).

Selected Publications 

Magnetism of Nanoparticles: Effect of the Organic Coating 

Nanomaterials, 11(7) (2021) 1787  

Size effects on the magnetic behavior of γ-Fe2O3 core/SiO2 shell nanoparticle assemblies

J. Magn. Magn. Matt. 522 (2021) 167570 

Effect of albumin mediated clustering on the magnetic behavior of MnFe 2O4 nanoparticles: experimental and theoretical modeling study

Nanotechnology 31 (2020) 025707

Effect of organic coating on the charge distribution of CoFe2O4 nanoparticles

 J. Al. Comp. 796 (2019) 9

Optimising the magnetic performance of Co ferrite nanoparticles via organic ligand capping 

Nanoscale 10 (2018) 21244

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