Functional carbon-based materials as drug delivery systems or bioimaging agents
Carbon-based nanomaterials modified with functional dendritic polymers were developed.1-3 Specifically, cationic hydrophilic dendritic polymers induce, through appropriate interactions, excellent and stable dispersions of carbon nanotubes and carbon nanodisks in aqueous media. These nanomaterials were physicochemically characterized by a variety of physicochemical methods and subsequently were evaluated as controlled release drug delivery systems.4-6
Additionally, functionalized highly fluorescent carbon dots have been developed and evaluated for mitochondrial subcellular localization and bioimaging agents.7
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- K.-M. Lyra, A. Kaminari, K. N. Panagiotaki, K. Spyrou, S. Papageorgiou, E. Sakellis, F. K. Katsaros, Z. Sideratou, Multi-Walled Carbon Nanotubes Decorated with Guanidinylated Dendritic Molecular Transporters: An Efficient Platform for the Selective Anticancer Activity of Doxorubicin. Pharmaceutics 13, 858 (2021). DOI:10.3390/pharmaceutics13060858.
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